Allicin powder is an organic sulfur compound extracted from the bulbs (garlic heads) of the Allium plant of the Allium family. It is also found in onions and other Allium plants. Its scientific name is diallyl thiosulfinate. , the chemical formula is C6H10OS2. The solid agent is a white to light yellow fluid powder, and the liquid agent is a light yellow to brown volatile oily liquid with a strong garlic smell. It decomposes during distillation and forms an oily precipitate when the aqueous solution is placed. Insoluble in glycerin, propylene glycol, etc., and can be mixed with ethanol, chloroform, ether, and benzene. Unstable to bases and stable to acids. The solution loses its effectiveness quickly when exposed to heat. Allicin has a strong antibacterial effect and can inhibit a variety of Gram-positive cocci and Gram-negative bacilli at very low concentrations. It also has inhibitory effects on molds, viruses, protozoa, pinworms, etc. It has obvious inhibitory effect on Escherichia coli and Shigella dysenteriae. It is used as insecticide and fungicide in agriculture, and also used in feed, food and medicine.
Allicin is unstable and loses its antibacterial activity when exposed to heat or alkali, but it is not affected by dilute acid. There is no allicin in fresh garlic, only alliin. When garlic is cut or crushed, the endogenous enzyme in garlic, alliinase, is activated, catalyzing the decomposition of alliin into allicin. Allicin can lower blood lipids, prevent hyperlipidemia, and block the formation of nitrosamines. Allicin can inhibit the reproduction of Shigella dysenteriae and Typhoid bacilli, and has obvious inhibitory and killing effects on Staphylococcus aureus and Pneumococcus aureus. Clinically, oral administration of allicin can treat animal enteritis, diarrhea, loss of appetite, etc. It is used as an insecticide and fungicide in agriculture, and is mainly used to prevent and control bacterial diseases of most crops and some fungal diseases.
CAS |
539-86-6 |
Molecular formula |
C6H10OS2 |
Molecular weight |
162.27 |
EINECS |
208-727-7 |
Melting point |
25 ºC |
Boiling point |
248.6 ºC |
Water solubility |
soluble |
Density |
1.148 g/cm³ |
Flash point |
104.2 ºC |
1. Inhibit the growth and reproduction of pathogenic microorganisms. It has been confirmed that the growth and reproduction of many bacteria such as gonococci, Staphylococcus aureus, and enterococci are inhibited by allicin. Allicin can also inhibit the growth and reproduction of fungi, viruses, and parasites. Garlic has a long history of being used to prevent and treat colds. In recent years, RCT studies have confirmed that allicin, the active ingredient in garlic, has the effect of preventing and treating colds.
2. It has the effect of lowering blood lipids and improving cardiovascular diseases. In addition, allicin also has a certain protective effect on the heart's pumping function and its own energy supply after heart failure.
3. Allicin has the function of lowering blood sugar.
4. Allicin can inhibit the synthesis of cholesterol in rat liver cells and improve liver damage caused by long-term high-fat diet in rats. In addition, allicin also has a preventive and therapeutic effect on autoimmune liver disease in rats.
5. Allicin has a strong antibacterial and anti-inflammatory effect, which can inhibit or kill a variety of cocci, bacilli, fungi, viruses, etc., and its bactericidal power is 100 times that of penicillin.
6. Allicin powder has inhibitory and killing effects on many fungi. Low concentrations of allicin mainly inhibit the growth of fungi, while high concentrations of allicin can completely kill fungi.
7. Allicin can improve the liver's detoxification ability and prevent poisoning by mercury, cadmium, lead, etc.
8. Antiviral and antiprotozoal effects.
In vitro tests have shown that allicin can effectively inhibit Coxsackievirus and echovirus. It has an inhibitory effect on histolytica, a significant inhibitory effect on Leishmania, and a significant killing effect on scrub typhus Rickettsia.
9. Improve animal quality.
Adding an appropriate amount of allicin during the breeding process, after being ingested by animals, can effectively stimulate the production of aroma-producing amino acids in meat, increase the production of the aroma component C3H5-S(0)-gene in animal meat or eggs, and thus enhance the flavor of animal meat. Or eggs taste more delicious.
10. Improve human immunity.
1. Garlic extract can be used in the pharmaceutical industry
2. Garlic extract can be used in the feed industry
Application effect in livestock production: Tests have shown that adding 50 mg, 67 mg, 84 mg, and 100 mg of allicin per kilogram to the diet of laying hens is more effective than laying hens fed feed without allicin. The egg production rates increased by 2.73%, 5.95%, 11.10%, and 7.83% respectively, with significant differences. Tests on dairy cows have shown that allicin can produce a strong natural aroma in dairy cow concentrates and has a strong food-attracting effect on dairy cows. Statistics show that adding allicin can increase the daily milk production of each cow by 2.28 kilograms and roughage. Feed intake can be reduced by 0.08 kg/day, and additional income can be increased by 6 to 8 yuan per day. Experiments on lactating sows found that allicin can increase pig feed intake. Experiments on piglets aged 15 to 28 days after weaning showed that when fed feed supplemented with 100 mg/kg allicin, the daily weight gain of piglets increased and the feed-to-meat ratio decreased. Compared with piglets fed feed without allicin, the difference was Significantly.
The role of allicin in fish production: Tests have shown that allicin has a strong attractant effect. Feeding tilapia with 500mg/kg allicin for 45 days increased the feed return by 11%, the comprehensive feed biological evaluation value increased by 12%, the survival rate increased by 2%-5%, and the weight gain rate also increased. The use of allicin has a good feeding attraction effect on crucian carp, grass carp, carp, etc. Use dried garlic heads with roots, grind them into powder with a meat grinder, heat and distill them, and obtain an oil-water mixture. After separation, add the obtained garlic oil at 0.008% of the weight of the bait and feed it to grass carp. The survival rate will increase by more than 15%. Feeding tilapia increases weight gain by 10%-15%.