| Customization: | Available |
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| CAS No.: | 70-18-8 |
| Formula: | C10h17n3o6s |
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Liposomal Glutathione is a form of glutathione supplementation that uses liposome encapsulation technology to enhance absorption and stability. Liposomes are tiny vesicles composed of a phospholipid bilayer that protect glutathione from degradation and improve its absorption rate in the digestive system.
1. Antioxidant effect
One of the benefits of glutathione is that it can effectively scavenge free radicals both directly and through enzymatic reactions. It can also maintain exogenous antioxidants such as vitamins C and E in their reduced (i.e. active) form. However, the efficiency of the glutathione redox system decreases with age.
2. Detoxification
Glutathione is a substrate for reactions catalyzed by glutathione S-transferases; a family of enzymes that catalyze the addition of glutathione to a substrate so that it can be eliminated. Conjugation with glutathione is an important Phase II detoxification pathway in the liver - glutathione is a hydrophilic (water-soluble) molecule that conjugates to various lipophilic (fat-soluble) physiological metabolites (e.g., estrogens) and xenobiotics, biotransforming them so that they can be excreted in the bile and then eliminated in the feces. Similarly, glutathione can also be conjugated and exported to the plasma for elimination through the urine. Therefore, in these reactions, glutathione is "lost" from the system rather than recycled. Glutathione can also participate in non-enzymatic conjugation with certain chemicals.
3. Neurodegenerative diseases
Dysregulation of glutathione homeostasis and alterations in the activity of glutathione-dependent enzymes are closely associated with neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.
Apoptosis (programmed cell death) is key to the progression of neurodegenerative diseases, and there is evidence that mitochondrial glutathione levels may play a key role in regulating this process.
Another mechanism by which glutathione affects neurodegenerative diseases is through the regulation of protein degradation pathways, which are involved in regulating cell survival.
4. Benefits of glutathione for eye health
Glutathione is present in high concentrations in the lens, especially in the epithelial layer, where it has many important functions, including helping to maintain lens transparency by preventing the formation of high molecular weight crystal aggregates, clearing xenobiotics, and preventing oxidative damage. A study of human lenses from birth to 92 years of age showed that glutathione levels decreased to 73% over the years, and oxidized glutathione levels (i.e., "consumed" glutathione) increased from 2% to 18%.
5. Benefits of Glutathione for Oral Health
Glutathione is an important redox regulator in saliva, and its maintenance is essential for periodontal health. Periodontal disease is a chronic inflammatory disease associated with increased inflammation caused by dental plaque biofilm (produced by bacteria), excessive production of ROS, and reduced antioxidant activity in saliva, leading to loss of periodontal and bone support.
Liposomal Glutathione Supplements
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