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Branched-chain amino acids (BCAAs) are a nutritional supplement that has been popular since about 1980. It is a collective name for three amino acids, including valine, leucine and isoleucine, because there is an methyl group in the molecular structure. The base side chain is called a branched chain amino acid. In recent years, branched-chain amino acids have been widely used in clinical or fitness industries due to their special effects.
1.Leucine
One of the main roles of leucine in the body is to help promote muscle growth at a molecular level. When sufficient amounts (approximately 3 grams) of leucine are consumed, molecular signals in muscle tissue are initiated, leading to muscle protein synthesis. Secondly, leucine can also stimulate the pancreas to release insulin. This helps reduce muscle protein breakdown and helps increase glycogen stores. Promoting muscle protein synthesis and triggering the insulin response, adequate leucine intake after exercise aids recovery.
2.Isoleucine
One recognized effect of isoleucine is to increase the amount of glucose absorbed by muscle cells. Isoleucine, taken together with leucine, may be more effective than taking either alone.
3.Valine
Valine is often considered a BCAA Bulk Powder of supplementary nature. This is mainly because valine's most well-known function is its self-conversion into glucose. It has been shown to be involved in some tissue repair, but does not appear to be as effective as leucine and isoleucine.
Branched-chain amino acids (BCAAs) - isoleucine, leucine and valine - are essential amino acids. BCAAs are derived from diet and protein hydrolysis, with a smaller contribution from de novo synthesis by the intestinal microbiota. Circulating BCAAs are used in protein synthesis or metabolism. Branched-chain amino acids are imported into mitochondria through the mitochondrial branched-chain amino acid carrier SLC25a44. The first two steps of the branched-chain amino acid catabolic pathway are mediated by the branched-chain aminotransferase (BCAT) and branched-chain alpha-ketoacid dehydrogenase (BCKDH) enzymes, shared by all three branched-chain amino acids. The catabolic pathway terminates in the tricarboxylic acid (TCA) cycle, but also produces important metabolic intermediates, such as the valine metabolite 3-hydroxyisobutyric acid (3-HIB) and monomethyl branched-chain fatty acids (mmBCFAs), They contribute to intracellular and paracrine signaling.
01 Provide energy for exercise
Like other amino acids, our main role is as a raw material for protein synthesis. Because it is mainly broken down in muscles, it can provide energy for exercise.
02 Enhance muscle synthesis ability and prevent muscle loss
One is to promote the release of insulin, allowing the muscles to absorb peripheral blood sugar to replenish energy, and at the same time promote the absorption of amino acids by the muscles. The second is to promote the release of growth hormone, help the body maintain a reasonable testosterone/cortisol ratio, and significantly enhance protein synthesis. While I promote anabolism, it also has very good anti-catabolic effects, helping to prevent protein breakdown and muscle loss.
03 Anti-fatigue effect
During exercise, tryptophan is converted into 5-hydroxytryptamine (5-HT), a central depressant that causes fatigue symptoms in the body. We and tryptophan are transported through the same carrier. When "competing" with tryptophan in the same channel, it can prevent the conversion of tryptophan, reduce the production of 5-hydroxytryptophan in the brain, and reduce 5-hydroxytryptophan. -The content of HT delays or prevents the release of "fatigue information", making the body more durable.
04 Synthesize protein
Regulates protein biosynthesis in the body. In muscle protein, 35% of essential amino acids are branched-chain amino acids.
05 Acts as a signaling factor and participates in energy metabolism
Branched-chain amino acids can serve as important signaling molecules, regulating cell growth and neurotransmitter synthesis. Involved in the metabolism of glucose and fatty acids.
06 Has immunomodulatory function
Branched Chain Amino Acids Powder can directly promote the recovery of immune cell function, improve the damaged immune system, and improve the nutritional status of patients with cancer and liver disease.
Branched-chain amino acids (BCAA) and other essential amino acids improve athletic performance because they support your strength and endurance goals.
BCAA supplements can increase circulating oxygen levels, which helps improve endurance and reduce fatigue during exercise.
Branched-chain amino acids also help maintain the body's glycogen stores (and other energy metabolites). Glycogen is stored in muscles and is the body's main source of fuel for energy production. During exercise, the body uses this store for energy.
When glycogen stores are depleted, people experience fatigue and optimal training performance is inhibited. However, branched-chain amino acids can help preserve glycogen stores during exercise, allowing people to sustain exercise for longer while reducing the effects of muscle damage during training.
They also reduce blood levels of creatine kinase and lactate dehydrogenase, both of which are muscle-damaging substances.
May reduce delayed onset muscle soreness (DOMS)
In addition to helping improve physical performance, branched-chain amino acid supplements have been shown to reduce muscle soreness. As you know, less muscle soreness means more time training.
Reduced levels of muscle soreness also contribute to BCAAs' ability to improve and optimize exercise performance.
When supplementing with BCAAs, muscle soreness is reduced and damaged muscle tissue fibers are repaired fairly quickly, allowing you to exercise more frequently without the need to rest in between.
The increased recovery time of BCAAs not only helps with muscle growth but also allows you to be in the gym more often so you can continue working toward your fitness goals.
Prevents muscle atrophy
Branched Chain Amino Acids Powder can also help prevent muscle atrophy, or the breakdown of muscle proteins, which of course takes away from muscle building.
There are many studies showing that supplementing with branched-chain amino acids can inhibit muscle protein breakdown.
This is important not only for athletes looking to improve muscle growth in the gym, but also for certain vulnerable groups, such as the elderly, or people with cancer or liver disease, who tend to have higher levels of malnutrition and muscle atrophy.
Since BCAAs make up approximately 35% of the amino acid profile of muscles, it is important to supplement with BCAAs to prevent muscle breakdown and promote muscle growth.
Can help people with liver disease
While most of the hype about BCAAs is within the fitness community, BCAAs actually have some clinical uses, such as helping people with cirrhosis (liver disease).
In hospital settings, BCAA supplements are given to patients with cirrhosis to help reduce liver damage and improve organ function.
Due to their special chemical structure, branched-chain amino acids can help regenerate healthy liver cells, thereby helping to improve liver function.
It's important to note that research does not support the use of branched-chain amino acids to improve liver health in people whose livers are already healthy.
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