High Quality Skin Whitening Phenylethyl Resorcinol Powder CAS 85-27-8

• CAS No.: 85-27-8
• Formula: C14h14o2
• Type: Cosmetic Raw Materials
• Appearance: Powder
• Colour: White
• Melting Point: 78 ºC
• Model NO.: YT0264
• Specification: 99%
• Trademark: YTBIO
• Origin: China

Product Description

Phenylethyl Resorcinol, molecular formula C 14H 14O 2, full chemical name: 4-(1-phenylethyl)-1,3-benzenediol, relative molecular weight 214.26, trade name 377, is a A white crystalline solid with low odor. Soluble in ethanol,  butylene glycol, and pentanediol, solubility in water is 265 mg/L at 25°C.


1. Effect on MITF and its signaling pathway: Phenylethylresorcinol can effectively inhibit the production of melanin and eumelanin. Phenylethyl resorcinol reduces the production of melanin by down-regulating the expression of MITF protein and its downstream tyrosinase-related proteins TRP1 and TRP2.
2. The effect on tyrosinase: phenylethyl resorcinol has an inhibitory effect on the enzyme catalytic process (it has inhibitory effect on tyrosinase monophenolase and diphenolase, and on tyrosinase diphenolase The inhibitory effect is non-competitive inhibition) and it is a tyrosinase inhibitor; it has no effect on non-enzyme catalytic processes.
3. Antioxidation: The oxidation-related protein nuclear factor E2-related transcription factor 2 (Nrf2) is a transcription factor that mediates oxidative stress. High concentrations of phenethylresorcinol can also downregulate genes and proteins related to oxidation, Nrf2 and NQO1.



Phenylethyl resorcinol is widely used in various whitening, anti-freckle and anti-aging products.