| Certification: | ISO, FDA |
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| Assay Method: | HPLC |
| Application Form: | Tablet, Capsule |
| Application: | Health Care Products, Medicine |
| State: | Powder |
| Test Method: | HPLC |
| Samples: |
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| Customization: |
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Ursolic acid is a kind of triterpenoids in natural plants. It has many biological effects, such as sedative, anti-inflammatory, antibacterial, anti-diabetic, anti ulcer, hypoglycemic and other biological effects. Ursolic acid also has obvious antioxidant function, so it is widely used as raw material of medicine and cosmetics.
| Product Name | Ursolic Acid | Appearance | White fine Powder |
| CAS No | 77-52-1 | Spec | 98% |
| MF | C30H48O3 | MW: | 456.7 |
| Grade | Cosmetic Grade, Medical Grade | Test Method | HPLC |
What is rosemary extract?
There are six main components of rosemary that offer the awesome qualities we'll soon want in every product! They are carnosic acid, carnosol, ursolic acid, rosmarinic acid, rosmaridiphenol, rosmanol. Rosemary also contains chlorogenic acid, caffeic acid, and tannins.
1. Ursolic Acid
A pentacyclic triterpene acid, ursolic acid is also found in apples, basil, bilberries, cranberries, elder flower, peppermint, lavender, oregano, thyme, and prunes. It offers anti-inflammatory, anti-microbial, and anti-oxidant properties to our creations. It may have some effect on blood circulation at the skin level, stimulating blood flow. It is called an anti-aging polyphenol because it may help restore skin's collagen bundles and elasticity. And it is showing promise as an anti-fungal ingredient. It is a more effective anti-oxidant than BHT.
Ursolic acid is alleged to be good for hair growth and prevention of scalp irritation, which is why you'll see rosemary included in many hair care products. The claim is that hair growth is encouraged by "stimulating peripheral blood flow in the scalp and activating hair mother cells". It is recommended for dandruff prone hair for the same reason. Again, more studies must be done, meaning this isn't a confirmed feature of ursolic acid.
Ursolic acid works in an interesting way - it actually forms an oil resistant barrier (I've seen it called a "waxy coating") on our skin, so we get a little occlusion from it, keeping the good stuff in and the damaging outside world outside! It is being tested as a burn and wound healer, due to the awesome nature of the anti-inflammatory action, and as a possible treatment for Candida albicans (yeast).
2. Carnosol
Carnosol is a diterpene found in rosemary that offers anti-oxidizing power more potent than BHT or BHA. It behaves as a free radical scavenger in our products. In rosemary extract, carnosol is slightly less effective than carnosoic acid as an anti-oxidant, but not by much (if carnosol is 1, then carnosoic acid rates a 1.2). It also has the ability to chelate iron in our products.
3. Carnosic Acid
Found in high levels in rosemary and sage, the carnosic acid is considered the main compound responsible for the high anti-oxidant levels of rosemary extract. It scavenges free radicals and hydrogen peroxide as well as hypochlorous acid (HOCl), a compound produced in our bodies at sites of inflammation. It also helps protect skin against UVA light, but I wouldn't use it as a sunscreen without testing!
When formulating with ingredients containing carnosic acid, we must add them in the cool down phase of our products as it is heat sensitive. It is also not great in aqueous solutions if said solution contains transitional metal ions. In other words, use distilled water. If you use tap water with some metal ions in it, it can send the carnosic acid into oxidation, which kinda defeats the purpose of using the ingredient in the first place. Or you can add some chelating ingredients (likeEDTA or citric acid) to bind the metal ions. It converts to carnosol or rosmanol after free radical attack.
4. Rosmaridiphenol
A very active anti-oxidant, it works about as well as or better than BHT or BHA in lard (there are conflicting results about which one it is better than, but suffice it to say it is a good anti-oxidant). It is oil soluble, so it is more effective in products containing some oils than products that are completely water based.
It can help reduce sebum production for particularly oily people, it can increase blood circulation in our skin, it can behave as an anti-microbial and anti-viral ingredient, it can offer mild analgesic properties, and it is an anti-inflammatory. Is it anti-aging? In the sense that it can help protect against UV damage, free radical damage, increase circulation - which could lead to improved skin tone - and it may help restore collagen and skin elasticity.
(1)Antioxidant and antineoplastic;
(2)Sedative,anti-inflammatory ,antibacterial;
(3)Reduce blood sugar;
(4)Antidiabetic,anti-ulcer.
Applications
1. Application in foods
Rosemary leaf and its oil traditionally used as spice in seasonings, meats, baked foods, etc.
Antioxidant and antiseptic used in lipids, dairy foods, oily foods, confections, baked foods, protect from deterioration and fading. Especially for fried foods, As it has excellent hot-resistant capacity, it can endure high temperature of 190ºC-240ºC.
Be used in water-soluble foods, beverage, drinks, aquatic products for antioxidant, antibacterial and antiseptic.
Compared with the synthetic antioxidants, rosemary is natural and green and safe, no side effects and toxicity,
Small dosage and non-influence to foods those demand higher requirement in color and flavor.
2. Application in cosmetics
Be widely used in cosmetics, excellent antioxidant ability, natural and non-toxic, no side effects and innoxious.
Possess astringency, can tighten skin.Rosemary ingredients can activate blood circulation, intensify vasoconstriction and hemangiectasis. Rosemary extracts can eliminate free radicals and inhibit degradation of elastin, thus help maintain elasticity and luster of skin.
Meliorate skin problems, such as pachylosis, desquamation and dryness.
Preventing microorganism and poisonous substance in epidermis cell from expansion.
Strengthening one's resistibility to exoteric sunshine, difference in temperature or humidity, so it also can be applied to suntan cream, make up base to protect sensitive, fragile and tender skin from harm of ultraviolet and computer radiation
Used in cosmetics, it is more stable than enzyme compounds SOD, better for eliminating freckles, inhibiting oxidation, increasing skin's elasticity and postponing senescence.
Enhance blood circulation of scalp, ameliorate state of losing hair, decrease occurrence of dandruff, stimulate growth of hair and nourish hair.
Used in bath water or aromatherapy it can accelerate circulation of blood, nourish skin, divert one from nervous state and revivify one's energy.
3. Appication in medication&health care
Improving the blood circulation;
Easing the nerve, calm the emotions;
Relieving stomach symptoms, such as greasiness, vomiting, flatulence, stomachache;
Relieving rheumatism and alleviate the pain
Regulating catamenia. Caution when use for pregnant
Adjusting blood pressure. Caution when use for hypertension
Anti-bacteria,diminishing inflammation, detoxification
Ameliorate rheum and chronic bronchitis
Prohibit acetylcholine from being decomposed, activate brain cells, improve reminiscence, good for senile cretinism even bath or skin application with rosemary oil.
Protect DNA from oxidation, restrain the formation of early tumor
Meliorate liver hyperaemia, alleviate hepatitis and hepatocirrhosis
Meliorate heart-throb hyperfunction and other handicaps of cordis nerves
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